Most Recent Molecular Biology and Biochemistry Articles.

  • MOLECULAR APROCHES IN CROP GROWTH REGULATION

    Growth is an irreversible change in biomass, size and number. In the development of plant growth, hormone plays a major role. Their action involved three major steps including perception, transduction and response. Signal perception involves the reaction of the hormone with a receptor site. In either event, the cell destined to respond to the hormone, known as the target cell, must be capable of detecting the presence of the hormone molecule either in the cell or in the fluids immediately surrounding the cell. The presence or absence of a particular receptor determines which cells are able to respond to the hormone. In the signal transduction and amplification stage, the activated hormone-receptor complex sets into motion a cascade of biochemical events that ultimately leads to the final, characteristic response. In the above process hormone binding protein plays a major role in the final response. They readily bind smaller molecules in a non-specific manner, especially when tissues are disrupted during isolation protocols.

    By: DEBASHISH HOTA
  • RNA EDITING IN DISEASES

    RNA-editing processes show great molecular diversity, and some appear to be evolutionarily recent acquisitions that arose independently. The diversity of RNA editing phenomena includes nucleobase modifications such as cytidine (C) to uridine (U) and adenosine (A) to inosine (I) deaminations, as well as non-templated nucleotide additions and insertions. RNA editing in mRNAs effectively alters the amino acid sequence of the encoded protein so that it differs from that predicted by the genomic DNA sequence. Identification of physiological significance of particular editing events have been identified in tumors, neuronal tissues, and brain.

    By: Ratanti Sarkhel
  • MODIFIED DOYLE AND DOYLE METHOD OF DNA ISOLATION FROM JACKFRUIT (Artocarpus heterophyllus Lam.)

    Modified Doyle and Doyle (1987) method for DNA extraction from the leaves of jackfruit.

    By: Ashok Chhetri
  • Spider silk: an important biomaterial

    Silk is a proteinaceous fiber. Web builder spiders have the most advanced toolkits for silk production. Spiders produce seven different forms of silk, each from different silk glands. Because of its several useful materialistic properties such as excellent strength, toughness, and elasticity as well as biodegradability and biocompatibility, it is emerging as useful biomaterial for its applications in biotechnology and biomedicine.

    By: kheta ram tak
  • PROLINE: BIOSYNTHESIS AND FUNCTIONS

    Proline is a proteogenic amino acid and accumulates both under stress and non-stress conditions as a beneficial solute in plants. Besides acting as an excellent osmolyte, proline plays major roles during stress, stabilization of proteins, membranes, and subcellular structures, and protecting cellular functions by scavenging reactive oxygen species. Proline can act as a signaling molecule to modulate mitochondrial functions, influence cell proliferation or cell death and trigger specific gene expression, which can be essential for plant recovery from stress.

    By: yamini tak
  • ANTINUTRITIONAL FACTORS IN FOODS

    Anti-nutritional factors are compounds which reduce the nutrient utilization and/or food intake of plants or plant products used as human foods and they play a vital role in determining the use of plants for humans. Antinutrients in plant foods are responsible for deleterious effects related to the absorption of nutrients and micronutrients. For maintaining the nutritional value of food, it is necessary that heating temperature and length of processing do not exceed the optimum temperature required to eliminate the effect of inhibitors.

    By: yamini tak
  • BIOACTIVE PEPTIDES

    The amino acid sequences encrypted in food protein may have a nutraceutical and pharmaceutical properties called as bioactive peptides (BAP). Source riches in protein content can be used for identification and characterization of BAP by high throughput technology after their release from sources.

    By: SARITA KUMARI
  • BRASSINOSTEROIDS: A NEW CLASS OF PLANT HARMONE

    Brassinosteroids (BR) are natural product similar in structure to animal steroid hormone and play important roles in plant growth and development. It is found at low levels in pollen, seeds, and young vegetative tissues throughout the plant kingdom with. They show distinct physiological effect on plant growth including improvement of stress tolerance in crop production.

    By: Chetan Kumar Nagar
  • Uncommon amino acids: Parts of certain protein and their role

    In all types of cells and their part, proteins are the most abundant biological macromolecules, which are constructed from the ubiquitous set of 20 amino acids, covalently linked in characteristic linear sequences. Because each of these amino acids has a side chain with distinctive chemical properties which decide the functional property of an amino acids. Apart from this universal set of amino acids there are some uncommon amino acids also found in certain proteins and plays an important role in protein function.

    By: Chetan Kumar Nagar
  • Quorum Sensing: Bacterially Speaking

    in attached file

    By: Raghuveer Singh
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